Articles Tagged With:
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Sulopenem Etzadroxil and Probenecid (Orlynvah)
The U.S. Food and Drug Administration has approved a combination of sulopenem and probenecid for the treatment of uncomplicated urinary tract infections.
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Epilepsy and Cardiovascular Events
This large prospective cohort study found that older adults with a lifetime history of epilepsy were more likely to experience cardiovascular events (CVEs), and that enzyme-inducing antiseizure medications (EIASMs) may account for a significant portion of this risk. The findings suggest a potential causal link between epilepsy treated with EIASMs and CVE, highlighting the need for careful medication selection in epilepsy management.
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Comparison of Postoperative Antibiotic Regimens for Complex Appendicitis
In a pragmatic, open-label, randomized trial conducted at 15 hospitals in the Netherlands, two days of postoperative intravenous antibiotics for complex appendicitis was found to be noninferior to five days in terms of infectious complications and mortality within 90 days.
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DOACs Can Safely Be Started Early After Atrial Fibrillation-Associated Stroke
In ischemic stroke associated with atrial fibrillation, early restart of anticoagulation with apixaban one to three days after ischemic stroke, compared to late restart (seven to 14 days), resulted in no significant differences between the groups in the primary outcome — a composite endpoint including recurrent ischemic stroke, symptomatic intracranial hemorrhage, and systemic embolism.
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Migraines: Which Came First, the Chocolate or the Craving?
Knowledge of the differentiation between the triggers for a potential migraine attack and the prodromal symptoms of an initiated migraine attack reveals strategies that decrease migraine disability. Recognition of migraine triggers allows for a modification of behavior to avoid precipitating an attack. Recognition of common migraine prodromal symptoms creates an early time window when rapid treatment enhances the therapeutic intervention’s efficacy.
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Osteoporosis: An Update for Primary Care Providers
Bones, as reservoirs of calcium and phosphorus, continuously remodel to maintain strength and function. However, suboptimal peak bone mass in young adulthood, excessive resorption of bone, or impaired bone formation during remodeling can result in osteoporosis. Among Caucasian adults ages 50 years and older in the United States, about 50% of women and 20% of men will experience an osteoporotic fracture in their remaining lifetime; however, fracture rates differ by ethnic/racial population and skeletal site. Annual fracture-related costs are expected to increase from $57 billion to more than $95 billion by 2040. Therefore, it is imperative that primary care providers address this challenge by implementing practices to screen patients for osteoporosis to prevent and/or treat the disorder and subsequent comorbidities.
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Abortion Bans Directly Affect OB/GYNs’ Mental Health and Burnout, Study Finds
Seven out of 10 OB/GYNs interviewed by researchers reported symptoms of anxiety and depression, directly related to the impact of the U.S. Supreme Court’s Dobbs v. Jackson Women’s Health Organization decision, according to a new study.
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People in Mississippi Blocked from Obtaining Preferred Contraceptives
New research shows how barriers affected women in Mississippi, where nearly two in five could not use their desired contraception.
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Fewer Facilities Offer Procedural Abortion After Dobbs Decision
The number of publicly advertising abortion facilities that provide procedural abortions dropped by 11% from 2021 to 2023, a new study finds.
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Online Pharmacies’ Role in Medication Abortion Access Is Critical, But Under Threat
New research demonstrates the importance of online pharmacies in direct-to-patient care and provision of medication abortion in the United States.